"Superman" actor Christopher Reeve, who became a committed campaigner for spinal cord research after being paralyzed in a riding accident nine years ago, died of heart failure, his publicist said on Monday.
Reeve, 52, went into a coma on Saturday when he suffered a heart attack during treatment for an infected pressure wound and died in Northern Westchester Hospital on Sunday afternoon without regaining consciousness, publicist Wesley Combs said.
Reeve's wife, Dana, issued a statement thanking "the millions of fans around the world who have supported and loved my husband over the years."
Reeve, confined to a wheelchair since his horseback riding accident in 1995, had in recent years used his celebrity status to mobilize funds and support for research into the treatment of spinal cord injuries, including the controversial stem cell research that has become an issue in the U.S. presidential election.
Reeve's family asked that donations be made in his honor to the Christopher Reeve Paralysis Foundation, formed in 1999 to boost collaboration between experts working on the problem and to encourage new approaches.
An accomplished rider who owned several horses, Reeve suffered multiple injuries including two shattered neck vertebrae when he was thrown from his horse at an equestrian event in Commonwealth Park in Virginia.
Doctors initially predicted he would never have any feeling or movement below his head. But his foundation's Web site, www.ChristopherReeve.org, said he had experienced a degree of recovery that his doctors considered "remarkable."
Reeve was a strong supporter of the research using human stem cells, which his foundation described as having "enormous therapeutic utility." Whether federal funds should be spent on such research is a issue dividing President Bush, who has limited such research, and his Democratic challenger, Sen. John Kerry of Massachusetts, who supports expanded efforts.